First ever fluoride-containing bioglass toothpaste wins FDA approval

High Fluoride Toothpaste, About | ACFF

Description: Fluoride dentifrices were first introduced in the 1950s. [1] The first fluoride dentifrice contained stannous fluoride and was first marketed in 1955. Since then many studies have investigated the level of dose and the form of fluoride that is optimum in dentifrice formulations. Higher caries reduction was reported in the 70s in clinical trials that investigated the potency of usin...

FDA drug approval summaries: fulvestrant.

Patients with hormone-sensitive breast cancer who have responded to tamoxifen may receive additional benefit from a second endocrine agent following progression or relapse after tamoxifen therapy. Fulvestrant (Faslodex((R)), ICI 182780, AstraZeneca Pharmaceuticals; Wilmington, Delaware) is a selective antagonist of estrogen designed to have no estrogenic effects. Lack of aqueous solubility led ...

FDA drug approval summaries: oxaliplatin.

The purpose of this report is to summarize information on oxaliplatin, a drug recently approved by the U.S. Food and Drug Administration. Information provided includes regulatory history, study design, efficacy and safety results, and pertinent literature references. A single, multicenter, randomized trial, enrolling 463 patients with metastatic colorectal carcinoma whose disease had recurred o...

Global affordability of fluoride toothpaste

OBJECTIVE Dental caries remains the most common disease worldwide and the use of fluoride toothpaste is a most effective preventive public health measure to prevent it. Changes in diets following globalization contribute to the development of dental caries in emerging economies. The aim of this paper is to compare the cost and relative affordability of fluoride toothpaste in high-, middle- and ...

On fluoride toothpaste – knowledge, attitudes and behaviour